Menopause and your Brain

Menopause and brain

Hormone surges and dips throughout menopause affect your brain as well as the rest of your body.

Here’s what happens and why, and how to cope.

The constant change of hormone levels during this time can have a troubling effect on emotions … leaving some women to feel irritable and even depressed.

Indeed, while everyone thinks of hormones as the chemicals that drive the women’s reproductive system, in truth, there are receptors for both estrogen and progesterone throughout the body.
When these hormone levels begin to decline, as they do in the months and years leading up to menopause, every system that has these hormone receptors registers the change, and that includes your brain.

And while most women can recite chapter and verse about what happens to their uterus or ovaries around this time (including problems like irregular bleeding or declining fertility), they hear very little about what happens when the hormone receptors in their brain begin running on empty!

What does happen? A disruption in an entire chain of biochemical activity, which in turn affects the production of mood-regulating chemicals, including serotonin and endorphins.

The end result: Mood swings, temper tantrums, depression, surprising highs followed by equally unexpected lows – and none of it seems to make any sense.

Your ovaries are failing and trying to keep up estrogen production. Some days they overshoot it, otherdays they can’t produce enough. Each time your hormones do a little dance, your brain chemistry has to compensate. When the change is small, that compensation occurs quickly, and you hardly notice any symptoms.

But when it’s more dramatic, an entire range of unexpected behaviors can come alive: You burst into tears when the bakery is out of rye bread. You weep uncontrollably during a greeting card commercial. You find that one minute you love your son’s new girlfriend and the next you have an overwhelming urge to push her face into a cream pie. And nothing seems to make any sense.

Menopausal Mood Swings: What to Do

The very first thing you must realize is that no, you’re not losing your mind. You may be acting crazy, feeling crazy, thinking crazy thoughts – but basically, you’re OK. And no, you don’t have to force yourself to sit on the “naughty stool” until perimenopause is over.

But there are a few key things you can try that might make a huge difference.

Among the most important: Reduce stress in your life.

How can this help? The effect of stress on hormone activity can be so profound that it is capable of inducing symptoms. Reducing stress can have the opposite effect.

Women who participated in organized relaxation studies saw a 30% decrease in their hot flashes, plus a significant drop in tension, anxiety, even depression. They also reported fewer mood swings and more stable emotions overall.

The good news: Reducing even small stresses in your life – or simply setting aside some time every day to relax and unwind – cannot only affect hormone balance but have a dramatic effect on your mood swings.

Another important suggestion: Whenever you do have an emotional upset, such as feeling very angry, step back, take a deep breath, and let a little time pass before you act on your dancing emotions. Chances are, when the mood swing passes – as it always does – you might not have the need to lash out at someone who probably doesn’t deserve it.
At the same time, if the mood passes and you still feel the same way, then by all means do what you must to clear the air. While many problems can temporarily seem bigger than they are during this time of life, real problems can also occur. But taking a little time between action and reaction may be all you need to know the difference.

Sleep Your Way to Happier Menopause

While hormones influence your mood and your temper, what can make everything seem worse is a lack of sleep. And if getting a good night’s rest seems to be getting harder during this time of life,you’re not alone.

A study published in the journal Menopause in 2001 observed that “insomnia is a frequently reported complaint in menopausal women.”

The reason: You may be sleeping – or wanting to sleep – but your estrogen levels are still up dancing all night long. And that continual action can interrupt healthy sleep.

This, in turn, reduces both the quantity and quality of your sleep, and when that happens hormones can go further off kilter, filling your waking hours with even more symptoms, particularly emotion-based problems.

But there are ways to induce better midlife sleep and in doing so help control some menopause symptoms. According to natural health expert Susan Lark, MD, herb teas of valerian root taken 45 minutes before bedtime might induce a deeper and more restful sleep. Passionflower or chamomile tea may have a similar effect, she says.

What you should avoid: Hot and spicy foods, as well as caffeine, at least several hours before bedtime. They may keep you awake and increase hot flashes, even in your sleep.

And relaxation can also have a positive effect on sleep. Taking 20 to 30 minutes to engage in a particularly relaxing activity right before going to bed may help you fall into a deeper sleep faster – and that means more and better quality rest can be yours.

Also, if hot flashes and “night sweats” are causing you to wake up, taking steps to sleep “cooler” can help. Sleepwear should be 50/50 cotton/polyester, and you should avoid nylon nighties or PJs. They can hold in body heat that may cause you to wake more easily if you do get a hot flash in your sleep.

Finally, sleeping with a window open and using light covers may provide the most help of all, since remaining cool during the night can help net you some better quality and more restful slumber. And that, in turn, may help control mood swings for a whole day.


To increase estrogen the natural way is a sure method of counteracting the symptoms of menopause. Take the Manna Menopause Support supplement each day and see the results for yourself. We also recommend a healthy diet and exercise. Read the Manna Diet e-book and try to make some healthy changes in your lifestyle.

Menopause Support

Print Friendly


  1. Mollize Hayward says

    Thank you for a very informative article.
    You have shed some light on my un-explainable moods and actions.

  2. Helen says

    A really great article – I’ve shared it on the Menopause Matters group on Facebook.