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Weight loss can be a lot more effective when you are burning fat and building lean muscle at the same time.

A number of studies have demonstrated that CLA reduces fat mass while increasing lean body mass.

Different types of fats have different purposes.

What is CLA (Conjugated linoleic acid)?

CLA is a naturally occurring fatty acid found in meat and dairy products, more specifically it is found in the meat from ruminant animals (e.g. animals such as cows and lamb that absorb nutrients in a specialised stomach by fermenting plant-based food, such as grass).

CLA is a family of 28 different isomers of linoleic acid. Linoleic acid is the shortest chain omega-6 polyunsaturated fatty acid (meaning they have more than one double bond in their backbone).

An isomer is a group of molecules with the same chemical formula (same number and type of atoms) but arranged into a different structure. In essence, CLA is a group of different variations of linoleic acid.

How does it work?

The documented benefit of CLA in reducing body fat is explained by two main theories:

  1. The first is the reduction of lipid uptake into adipocytes (fat cells) by inhibition of a specific enzyme called lipoprotein lipase. This mechanism is facilitated predominantly by the t10 isomer of CLA
  2. The second mechanism considered is the proposed benefit of CLA in reducing the accumulation of triacylglycerol in fat cells. Triacylglycerol is a blood lipid which enables transfer of glucose and fat from the liver.

In animal model studies on mice, CLA was found to reduce accumulation of triacylglycerol in fat cells. This benefit was also seen in cultures of human cells with the t10 isomer.

A separate study demonstrated that fat loss in rats fed a CLA supplement is due to a reduction in the size of fat cells by 15 to 29% compared to controls.

These results indicate the CLA can reduce both synthesis and storage of fat cells, as such reducing levels of body fat in both animal and human laboratory models.

Benefits of Conjugated Linoleic Acid (CLA)

  • May help treating Cancer, Asthma, Cardiovascular disease, High blood pressure, High cholesterol and triglycerides and Osteoporosis
  • May improve Immune Function
  • May assist in weight loss
  • Could help reduce body fat

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How to take CLA?

Dosage

3 grams of CLA should be taken every day. This is preferably by taking either 1 softgel three times daily with every meal, or 3 softgel with breakfast every morning. This dosage is recommended for both adults and children, especially those fighting obesity. CLA is considered safe for use with your medication.

A healthy diet such as the Manna Diet and regular exercise is highly recommended for effective and healthy weight loss.

Who can use it?

CLA is safe for anyone to use. We are not recommending it for children younger than 5 years.

Why CLA is beneficial for healthy weight loss and the fighting of disease

There are different types of fat found in our daily diet, while others are manufactured in the body. Conjugated Linoleic Acid or CLA is a unique type of fatty acid that is primarily found in beef and dairy products.

CLA is not manufactured in the body, and must, therefore, be obtained from a healthy diet. While many fats are simply used to produce energy, CLA also provides several powerful health benefits to the body. Numerous studies have shown that CLA can help with effective and healthy weight loss. This has made it one of the most popular weight loss supplements in the world.

Aside from weight loss, CLA also has many other health benefits. As it works mainly by reducing the deposition of fat in the body, it also helps to boost the immune system at the same time. Different studies conducted on humans, animals and in laboratories have shown CLA as highly effective at combating the following health conditions:

  • Cardiovascular disease
  • Immune system invaders
  • Inflammation
  • High blood pressure
  • High cholesterol and triglycerides
  • Osteoporosis

Other illnesses, in which CLA is beneficial, include:

  • Cancer

Research conducted on animals have shown that tumours could be reduced by as much as 50% by CLA. This is achieved by taking 0.5% of CLA in the diet. These types of cancers include:

  • Lung cancer
  • Breast cancer
  • Colorectal cancer
  • Stomach cancer
  • Skin cancer
  • Asthma

Leukotrienes, a type of fatty acid of the immune system, are produced in much higher levels in persons suffering from asthma. These molecules are over 1000 times more powerful at causing bronchial constriction than histamine. They are produced when the enzyme 5-lipoxygenase (5-lipox) acts on Arachidonic acid (AA), a fatty acid found in the body. CLA combats asthma by converting into the potent anti-inflammatory compounds DHA and EPA. This helps fight inflammation caused by 5-Lipox and AA, without damaging your arteries.

  • Insulin resistance

Tests conducted on mice with type 2 diabetes have shown that CLA mimics the action of synthetic diabetic drugs. It increases the effect of insulin while reducing blood sugar levels. The same beneficial effects have been observed in humans after 8 weeks of CLA use.

  • Body fat composition

Research studies on humans taking CLA have shown great results in the lowering of body fat composition. The results are even better when CLA use is combined with regular physical exercise. Studies in animals have also indicated that CLA reduces body fat and increases lean body mass as well.

According to a study published in the American Journal of Clinical Nutrition, people taking 3.2 grams of CLA daily lost 500g of body fat per month. This was in contrast to those taking a placebo. Other studies show that CLA lowers body fat and preserves muscle, and might also increase your metabolic rate.

How safe is CLA?

Although conjugated linoleic acid supplements are considered safe, excessive intake of CLA can lead to stomach and intestinal problems, nausea and diarrhoea.

Can I use it with other medication?

If you take any medicines regularly, talk to your doctor before you start using CLA supplements. They may interact with drugs for schizophrenia and other mental disorders as well as with blood thinners or antihypertensive.

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Research

  1. Efficacy of conjugated linoleic acid for reducing fat mass: a meta-analysis in humans1,2 – Am J Clin Nutr May 2007 vol. 85 no. 5 1203-1211
  2. A review on effects of conjugated linoleic fatty acid (CLA) upon body composition and energetic metabolism – Journal of the International Society of Sports Nutrition2015